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Christine Larson, Assistant Professor

Prof. Christine Larson

Office: Garland Hall, Room 217
Phone: 414-229-4996
e-mail: larsoncl@uwm.edu
Web Site: http://www.uwm.edu/~larsoncl

Degree:
Ph.D., University of Wisconsin-Madison, 2003

Research Interests:
My laboratory, the Affective Neuroscience Laboratory, is dedicated to understanding the neural bases of healthy and pathological emotional processing. Currently, my research program has two main foci: individual differences in emotional processing which confer risk for psychopathology, particularly anxiety or depression, and characterizing the nature of stimuli in the environment which serve as signals for different types of emotions. I use neuroimaging, psychophysiological, behavioral, and self-report tools to examine affective processing broadly, including the time course, intensity, and regulation of affective responses. As such, my work sits at the intersection of emotion, psychopathology, and neuroscience research.

Current research questions include:

  • Can the time course of affective response usefully index individual differences related to risk and resilience for psychopathology?
    • Are symptoms of anxiety and depression associated with prolonged experience of negative affect? What are the neural correlates of this phenomenon?
    • Are some forms of anxiety associated with rapid onset of fear? Can this be identified at the level of the brain?
    • What, if anything, distinguishes worry and rumination? Are there separable neural instantiations of these two processes?
  • Can visual signals of threat and happiness be reduced to fundamental underlying properties, such as their underlying geometry? Do brain regions implicated in recognition and experience of threat and happiness respond to simple geometric shapes?

Recent Publications:
Larson, C.L., Aronoff, J., & Stearns, J. (in press). The shape of threat: Simple geometric forms evoke rapid and sustained capture of attention. Emotion.

Burt, S.A., & Larson, C.L. (2007). Differential affective responses in those with aggressive versus non-aggressive antisocial behaviors. Personality and Individual Differences, 43, 1481-1492.

Larson, C.L., Nitschke, J.B., & Davidson, R.J. (2007). Common and distinct patterns of affective response in dimensions of anxiety and depression. Emotion, 182-191.

Larson, C.L., Schaefer, H.S., Siegle, G.J., Jackson, C.A.B., Anderle, M.J., & Davidson, R.J. (2006). Fear is fast in phobic individuals: Amygdala activation in response to fear-relevant stimuli. Biological Psychiatry, 60, 410-417.

Larson, C.L., Ruffalo, D., Nietert, J., & Davidson, R.J. (2005). Stability of emotion-modulated startle during short and long picture presentation. Psychophysiology, 42, 604-610.

Nitschke, J.B., Larson, C.L., Smoller, M.J., Navin, S.D., Pederson, A.J.C., Ruffalo, D., Mackiewicz, K.L., Gray, S.M., Victor, E., & Davidson, R.J. (2002). Startle potentiation in aversive anticipation: Evidence for state but not trait effects. Psychophysiology, 39, 254-258.

Davidson, R.J., Putnam, K.M., Larson, C.L. (2000). Dysfunction in the neural circuitry of emotion regulation-A possible prelude to violence. Science, 289, 591-594.

Jackson, D.C., Malmstadt, J.R., Larson, C.L., & Davidson, R.J. (2000). Conscious suppression and enhancement of emotion. Psychophysiology, 37, 515-522.

Larson, C.L., Ruffalo, D., Nietert, J., & Davidson, R.J. (2000). Temporal stability of the emotion-modulated startle response. Psychophysiology, 37, 92-101.