Basic Biological Safety – Principles and Practices
Risk Group 1 – Biosafety Level 1 (BL1)
Agents at this level are those which are well-characterized and which are not known to consistently cause disease in healthy adults humans or animals.
- E. coli K-12 (non-pathogenic lab strain)
- Saccharomyces serevisiae
- Bacillus subtillis
- Candida albicans
RG1 agents are so numerous they are not specifically listed in Appendix B of the NIH Guidelines.
Recombinant RG1 agents can be modified so that they can infect humans and can be used to introduce foreign genes. Increased precautions may be appropriate for some recombinant RG1 experiments.
Features of BL1
Facility requirements are minimal with work on an open lab bench; however, at a minimum Standard Microbial Practices must be used.
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Updated November 27, 2007 by SAK